Prevention+ aims to address gender inequality by promoting masculinities based on equality, non-violence and care-giving, and by focusing on boys and men, and girls and women, as agents of change. The long-term objectives of this five-year program are to contribute to a gender just society which is free of gender-based violence (GBV). Prevention+ aims to transform social norms that drive GBV, and contribute to related changes in legislation, policies and practices of governments and other service providers. Rutgers, Promundo, and Sonke Gender Justice, along with local partners, will work with institutions and male and female adolescents and adults across Indonesia, Pakistan, Uganda, Rwanda and selected MENA countries. Women’s rights organizations are essential partners of this program to support activities and advocate for change. The MenEngage Alliance will further promote Prevention+ objectives internationally through its network and policy advocacy. The program is evidence-based; it has been developed on the basis of research findings that show that well-designed gender-transformative programs with both sexes of different age groups are highly effective in order to underpin the positive transformation of rigid gender norms, and contribute to a society free of GBV. Prevention+ is funded by the Government of the Netherlands.